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Index > Protein center > Mat1a(Gene name) > Rat
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  • Mat1a (Gene name),
  • S-adenosylmethionine synthase isoform type-1 (Protein name ),  METK1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mat1a(Ams1);
    Protein name:
    S-adenosylmethionine synthase isoform type-1(AdoMet synthase 1);
    Alternative:
    Methionine adenosyltransferase I/III(MAT-I/III);Methionine adenosyltransferase 1(MAT 1);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotetramer (MAT-I) or homodimer (MAT-III).
    Function:
    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    397
    Sequence:
    50:
    MNGPVDGLCD | HSLSEEGAFM | FTSESVGEGH | PDKICDQISD | AVLDAHLKQD | 
    100:
    PNAKVACETV | CKTGMVLLCG | EITSMAMIDY | QRVVRDTIKH | IGYDDSAKGF | 
    150:
    DFKTCNVLVA | LEQQSPDIAQ | CVHLDRNEED | VGAGDQGLMF | GYATDETEEC | 
    200:
    MPLTIVLAHK | LNTRMADLRR | SGVLPWLRPD | SKTQVTVQYV | QDNGAVIPVR | 
    250:
    VHTIVISVQH | NEDITLEAMR | EALKEQVIKA | VVPAKYLDED | TIYHLQPSGR | 
    300:
    FVIGGPQGDA | GVTGRKIIVD | TYGGWGAHGG | GAFSGKDYTK | VDRSAAYAAR | 
    350:
    WVAKSLVKAG | LCRRVLVQVS | YAIGVAEPLS | ISIFTYGTSK | KTERDELLEV | 
    397:
    VNKNFDLRPG | VIVRDLDLKK | PIYQKTACYG | HFGRSEFPWE | VPKKLVF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat AdoMet synthase 1
    Cat.:
    E0246r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat AdoMet synthase 1
    Cat.:
    E0246m
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat AdoMet synthase 1
    Cat.:
    E0246h
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat AdoMet synthase 1
    Cat.:
    E0246b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat AdoMet synthase 1
    Cat.:
    U0246m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat AdoMet synthase 1
    Cat.:
    U0246r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat AdoMet synthase 1
    Cat.:
    U0246h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat AdoMet synthase 1
    Cat.:
    U0246b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat AdoMet synthase 1
    Polyclonal Antibody for Rat AdoMet synthase 1
    Cat.:
    P0246Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AdoMet synthase 1
    Cat.:
    P0246Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AdoMet synthase 1
    Cat.:
    P0246Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat AdoMet synthase 1
    Monoclonal Antibody for Rat AdoMet synthase 1
    Monoclonal Antibody for Rat AdoMet synthase 1
    Monoclonal Antibody for Rat AdoMet synthase 1
    Protein for Rat AdoMet synthase 1
    Protein for Rat AdoMet synthase 1
    Protein for Rat AdoMet synthase 1
    Protein for Rat AdoMet synthase 1

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    Linearity
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    References
    1. 1.
      "Isolation of a cDNA encoding the rat liver S-adenosylmethionine synthetase."
      Horikawa S. , Ishikawa M. , Ozasa H. , Tsukada K.
      Eur. J. Biochem.184:497-501(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: Wistar.
      tissue: Liver.
    2. 2.
      "Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the Mr deduced from the cDNA sequence and the purified enzyme."
      Alvarez L. , Asuncion M. , Corrales F. , Pajares M.A. , Mato J.M.
      FEBS Lett.290:142-146(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Spleen.
    4. 4.
      "Nitric oxide inactivates rat hepatic methionine adenosyltransferase In vivo by S-nitrosylation."
      Ruiz F. , Corrales F.J. , Miqueo C. , Mato J.M.
      Hepatology28:1051-1057(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION
    5. 5.
      "Methionine adenosyltransferase S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target thiol."
      Perez-Mato I. , Castro C. , Ruiz F.A. , Corrales F.J. , Mato J.M.
      J. Biol. Chem.274:17075-17079(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION AT CYS-121
    6. 6.
      "Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase."
      Martinez-Chantar M.L. , Pajares M.A.
      Eur. J. Biochem.267:132-137(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
    7. 7.
      "Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism."
      Gonzalez B. , Pajares M.A. , Hermoso J.A. , Guillerm D. , Guillerm G. , Sanz-Aparicio J.
      J. Mol. Biol.331:407-416(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS)
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